Daranee RajtboriraksSiriruk NakornchaiPanit BunditsingRudee SuraritPiyarat IemjarernMahidol University2018-07-242018-07-242004-01-01Pediatric Dentistry. Vol.26, No.1 (2004), 63-66016412632-s2.0-2342627304https://repository.li.mahidol.ac.th/handle/123456789/21302Purpose: The objectives of this study were to investigate the fluoride levels in plaque and saliva before and after applying fluoride-containing pit and fissure sealants, and compare the fluoride release of 2 types of sealants at the different time intervals. Methods: Eighteen children ages 6 to 9 years were randomly divided into 2 groups: Group 1 - sealant containing fluorosilicate glass (Helioseal-F); and group 2-sealant containing methacryloyl fluoride-methyl methacrylate copolymer (Teethmate-F). Saliva and plaque samples were collected before and after the sealants were placed on their 4 first permanent molars. Fluoride levels were determined using the microdiffusion method. Fluoride concentrations before and after placing the sealants were analyzed by paired t test, and the fluoride concentrations between the 2 sealants were compared by t test, with the level of significance at 0.05. Results: There was no significant difference between salivary fluoride levels before and after sealant placement application in both groups. The plaque fluoride level of Helioseal-F group at 24 hours was significantly higher than the baseline level (P=.03), and was not different afterwards. The plaque fluoride levels after sealant with Teethmate-F were not significantly different when compared to the baseline. However, there were no significant differences between salivary and plaque fluoride levels of the 2 groups at different time intervals. Conclusions: The groups sealed with sealant containing fluorosilicate glass showed significant increase of plaque fluoride level only at 24 hours after sealant placement.Mahidol UniversityDentistryMedicineArticleSCOPUS