Uraporn VongvatcharanonSurapong VongvatcharanonNisaudah RadenahmadPornpimol KiriratPranom IntasaroPrasert SobhonTerry ParkerPrince of Songkla UniversityMahidol UniversityUniversity of Nottingham2018-07-242018-07-242004-01-01JRAAS - Journal of the Renin-Angiotensin-Aldosterone System. Vol.5, No.3 (2004), 135-140147032032-s2.0-6444241718https://repository.li.mahidol.ac.th/handle/123456789/21245Apoptosis and angiotensin II (Ang II) have been suggested as possible causes of arrhythmias. In addition, Ang II via Ang II type I (AT1-) receptors, has been demonstrated to induce cardiomyocyte apoptosis. The transgenic m(Ren-2)27 (TG) rat carries the additional Ren-2 gene, the expression of which results in an increase in cardiac Ang II, thus potentially affecting the cell growth/death equilibrium. In this study we have investigated the effect of Ang II, via AT1-receptors, on mediating apoptosis in a cardiac conduction system (SA node and AV nodes).Mahidol UniversityBiochemistry, Genetics and Molecular BiologyMedicineArticleSCOPUS10.3317/jraas.2004.030