May HoH. Kyle WebsterPongsri TongtaweKovit PattanapanyasatWilliam P. WeidanzMahidol UniversityArmed Forces Research Institute of Medical Sciences, ThailandDrexel University2018-06-142018-06-141990-01-01Immunology Letters. Vol.25, No.1-3 (1990), 139-141016524782-s2.0-0025090884https://repository.li.mahidol.ac.th/handle/20.500.14594/15970The T cell receptor γδ is normally e xpressed on a small percentage of peripheral lymphocytes. Although the role of γδ T cells in the physiologic immune response is still unknown, there is accumulating evidence that γδ T cells may participate in the immune response to mycobacterial and other infectious organisms. In this study, we have quantitated the number of circulating γδ T cells during acute Plasmodium falciparum malaria. The results indicate that γδ T cells are elevated during the acute infection and remain elevated for at least 4 weeks during convalescence. T cells may participate in the immune response against P. falciparum by functioning as non-MHC restricted cytotoxic cells against intraerythrocytic parasites. Alternatively, lymphokines may be produced on antigen stimulation which may have antiparasitic activity. © 1990.Mahidol UniversityImmunology and MicrobiologyMedicineArticleSCOPUS10.1016/0165-2478(90)90105-Y