Suphaphat KwonpongsagoonChanokwan KatasilaPornpimol KongtipSusan WoskieUniversity of Massachusetts LowellMahidol UniversityCenter of Excellence on Environmental Health and Toxicology (EHT)2022-08-042022-08-042021-03-02International Journal of Environmental Research and Public Health. Vol.18, No.6 (2021), 1-1916604601166178272-s2.0-85102489333https://repository.li.mahidol.ac.th/handle/20.500.14594/77056The herbicides glyphosate, paraquat, and 2,4-D play a significant role in Thailand. This paper is among the first study to describe the intensity of herbicide application and illustrate how the herbicides are extensively distributed over a large area through both agricultural and nonagri-cultural practices. Using a quick, economical, and simplified method of Material Flow Analysis together with spatial analysis, better data for the analysis of possible environmental herbicide con-tamination, human exposure, and related health risks for the general public and applicators can be developed. The findings from this study showed that in the study province, about 2.2 million kg of the active ingredients from the three targeted herbicides is applied annually. Pathway flow modeling with spatial analysis identified several local hotspots of concern based on the type of herbicide and crop/activity where it was used. Cassava planting was found to have the highest herbicide application activity, whereas rice cultivation was the major contributor of total herbicide mass, due to the wide area of cultivation in the province. The herbicide most likely to be applied at rates higher than recommended was 2,4-D, particularly on cassava and sugarcane farms.Mahidol UniversityEnvironmental ScienceMedicineArticleSCOPUS10.3390/ijerph18063046