Akihiro TakeshitaHiroko WatanabeChiaki YamadaVeera Sekaran NadarajanParichart PermpikulAttapong SinkitjasubChan Pui Ha NatalieShuming ZhaoKyou Sup HanDae Won KimJang Soo SuhHyun Ok KimKinuyo KawabataKen IshimaruNaoki OhtomoNaotomo YamadaYutaka TomodaKimiko YurugiHitoshi OhtoJapanese Red Cross Medical CenterKyungpook National University HospitalPrince of Wales Hospital Hong KongThird Military Medical UniversitySaga UniversityYonsei University College of MedicineSungKyunKwan University, School of MedicineTaksin HospitalUniversity of Malaya Medical CentreFaculty of Medicine, Siriraj Hospital, Mahidol UniversityKyoto University HospitalAsahikawa Medical UniversityHamamatsu University School of MedicineTokyo Medical and Dental UniversityFukushima Medical UniversitySeegene Medical Foundation2020-12-282020-12-282020-10-01Transfusion and Apheresis Science. Vol.59, No.5 (2020)18781683147305022-s2.0-85092514720https://repository.li.mahidol.ac.th/handle/20.500.14594/60590© 2020 Elsevier Ltd As an East-Asian international study, we evaluated erythrocyte alloimmunity by gender and history of transfusion or pregnancy. In total, data from more than 1,826,000 patients were analyzed, from whom 26,170 irregular erythrocyte antibodies were detected in 22,653 cases. Antibody frequencies in these cases were as follows: anti-E, 26.8%; anti-Lea, 20.0%; anti-P1, 7.1%; anti-M, 6.4%; anti-Mia, 5.6%; anti-c + E, 5.6%; anti-Leb, 4.6%; anti-D, 2.8%; anti-Fyb, 2.6%; anti-Lea+Leb, 2.5%; anti-Dia, 2.0%; and others. For pregnant patients, anti-D (12.7%) was statistically more frequent. For transfused patients, anti-E (37.3%), anti-c + E (9.5%), anti-C + e (3.3%) and anti-Jka (3.1%) were significantly more frequent.Mahidol UniversityMedicineReviewSCOPUS10.1016/j.transci.2020.102944