Successful treatment of spindle cell hemangiomas in a patient with Maffucci syndrome and review of literatures

Ramrada LekwuttikarnJames ChangJoyce M.C. TengStanford University School of MedicineFaculty of Medicine, Ramathibodi Hospital, Mahidol UniversityStanford University Medical Center2020-01-272020-01-272019-05-01Dermatologic Therapy. Vol.32, No.3 (2019)15298019139602962-s2.0-85065214080https://repository.li.mahidol.ac.th/handle/20.500.14594/51690© 2019 Wiley Periodicals, Inc. Maffucci syndrome is a rare genetic disease due to somatic mutation of IDH1 gene. Currently there is no medical treatment available for spindle cell hemangioma associated with this disorder. Here we report successful management of these hemangiomas using sirolimus in combination with surgery.Mahidol UniversityMedicineSuccessful treatment of spindle cell hemangiomas in a patient with Maffucci syndrome and review of literaturesArticleSCOPUS10.1111/dth.12919