Gunter KarigNopporn ThasanaTimothy GallagherUniversity of BristolChulabhorn Research InstituteMahidol University2018-07-242018-07-242002-05-20Synlett. No.5 (2002), 808-810093652142-s2.0-0036250925https://repository.li.mahidol.ac.th/handle/20.500.14594/20129Halide-directed deprotonation and Li-Zn exchange of 4-bromopyridine 4 provides organozinc 6, which undergoes Pd-mediated coupling to give the 3-aryl-4-bromopyridines 7. Further substitution is achieved to provide the 3,4-disubstituted pyridines 8 and 9, and the 3,4,5-trisubstituted variants 10.Mahidol UniversityChemistryArticleSCOPUS