Kittipoom ChinhiranCharussri LeeyaphanFaculty of Medicine, Siriraj Hospital, Mahidol University2019-08-282019-08-282018-03-01Siriraj Medical Journal. Vol.70, No.2 (2018), 182-183222880822-s2.0-85051585477https://repository.li.mahidol.ac.th/handle/20.500.14594/46862© 2018, Faculty of Medicine Siriraj Hospital, Mahidol University. Objective: To report a case of posaconazole induced diffuse lentigines. Case presentation: A 57-year-old Thai male with acute promyelocytic leukemia who received chemotherapy and antifungal drug prophylaxis then appeared abruptly generalized multiple discrete well-defined brownish macules on face, lips, trunk, back, both arms, forearms, both thighs, legs, both palms and soles about eight days after received posaconazole. Conclusion: Multiple lentigines could be found in patients who received immunosuppression or immunomodulation, and antifungal drugs such as voriconazole.Mahidol UniversityMedicineArticleSCOPUS10.14456/smj.2018.30