Songsak PetmitrS. NuchfaongP. ChaksangchaichotW. PongstapornP. SutinontT. LimsilaP. PunyaritMahidol University2018-07-242018-07-242002-04-25Journal of Experimental and Clinical Cancer Research. Vol.21, No.1 (2002), 31-35039290782-s2.0-0036225992https://repository.li.mahidol.ac.th/handle/20.500.14594/20067Genetic alterations at 12 dinucleotide repeat loci located on human chromosomes 2, 3, 12, and 17 have been analyzed in non-small cell lung cancer from Thai patients. Seventeen out of 30 cases (57%) harbored the microsatellite alterations. Of the 30 cases, 19 patients had a history of tobacco smoking, of whom 14 (74%) were in the group with microsatellite alterations, whereas 3 out of 11 non-smokers (26%) had these alterations. The frequency of microsatellite alterations among smokers was significantly higher than it was in non-smokers (P = 0.01 Fisher's exact test; odds ratio; 7.47).Mahidol UniversityBiochemistry, Genetics and Molecular BiologyMedicineArticleSCOPUS