Vichai ReutrakulPornsiri LeewanichPatoomratana TuchindaManat PohmakotrThaworn JaipetchSamaisukh SophasanThawatchai SantisukMahidol UniversityThailand Royal Forest Department2018-07-242018-07-242003-11-01Planta Medica. Vol.69, No.11 (2003), 1048-1051003209432-s2.0-0347950974https://repository.li.mahidol.ac.th/handle/20.500.14594/20681Two new naturally occurring coumarins, isomesuol (1) and mammearin A (2), together with nine known Mammea coumarins 3-11 were isolated from the EtOAc extract of the leaves and twigs of Mammea harmandii. Coumarins 1, 3 and 4 showed cytotoxicity against a panel of mammalian cancer cell lines. Their structures were determined by spectroscopic methods. The assignments of13C-NMR signals of isomesuol (1), which was isolated for the first time as a natural product, have been revised.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1055/s-2003-45154