Manat PohmakotrDarunee SoorukramPatoomratana TuchindaSamran PrabpaiPalangpon KongsaereeVichai ReutrakulMahidol University2018-07-242018-07-242004-05-24Tetrahedron Letters. Vol.45, No.22 (2004), 4315-4318004040392-s2.0-2342498603https://repository.li.mahidol.ac.th/handle/20.500.14594/21185The vicinal dianions derived from chiral succinic acid derivatives, 1,4-bis[(4R,5S)-3,4-dimethyl-2-oxo-5-phenylimidazolidin-1-yl]butane-1,4-dione and 1,4-bis[(4S,5R)-3,4-dimethyl-2-oxo-5-phenylimidazolidin-1-yl]butane-1,4- dione react with arylmethyl bromides with high diastereo- and regio-selectivity to provide the corresponding chiral α-arylmethylated succinic acid derivatives; the (R)-products are converted into (R)-β-arylmethyl-γ- butyrolactones and (R)-α-arylmethyl-γ-butyrolactones. © 2004 Elsevier Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1016/j.tetlet.2004.04.008