Kei Ichi IshidohHiroshi KinoshitaYasuhiro IgarashiFumio IharaTakuya NihiraOsaka UniversityToyama Prefectural UniversityInstitute of Fruit Tree and Tea Science, NAROMahidol University2018-11-092018-11-092014-01-01Journal of Antibiotics. Vol.67, No.6 (2014), 459-46318811469002188202-s2.0-84903537170https://repository.li.mahidol.ac.th/handle/20.500.14594/34916Verlamelin and its new derivative (verlamelin B) were isolated from fermentation broth of entomopathogenic fungus Lecanicillium sp. HF627. As the structural elucidation of verlamelin so far was only preliminary, we studied and determined the absolute structure of these two compounds to be cyclo(5S-hydroxytetradecanoic acid-D-alloThr/Ser-D-Ala-L-Pro-L-Gln-D-Tyr-L-Val). This is the first study that precisely analyzed the structure of verlamelin. © 2014 Japan Antibiotics Research Association All rights reserve.Mahidol UniversityPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1038/ja.2014.22