Massimo SartelliGian L. BaiocchiSalomone Di SaverioFrancesco FerraraFrancesco M. LabricciosaLuca AnsaloniFederico CoccoliniDeepak VijayanAshraf AbbasHariscine K. AbongwaJohn AgboolaAdamu AhmedLali AkhmeteliNezih AkkapuluSeckin AkkucukFatih AltintoprakAurelia L. AndreievDimitrios AnyfantakisBoiko AtanasovMiklosh BalaDimitrios BalalisOussama BaraketGiovanni BellanovaMarcelo BeltranRenato Bessa MeloRoberto BiniKonstantinos BouliarisDaniele BrunelliAdrian CastilloMarco CataniAsri Che JusohAlain Chichom-MefireGianfranco CocorulloRaul CoimbraElif ColakSilvia CostaKoray DasSamir DelibegovicZaza DemetrashviliIsidoro Di CarloNadezda KiselevaTamer El ZalabanyMario FaroMargarida FerreiraGustavo P. FragaMahir GachabayovWagih M. GhnnamTeresa Giménez MaurelGeorgios GkiokasCarlos A. GomesEwen GriffithsAli GunerSanjay GuptaAndreas HeckerElcio S. HiranoAdrien HodonouMartin HutanOrestis IoannidisArda IsikGeorgy IvakhovSumita JainMantas JokubauskasAleksandar KaramarkovicSaila KauhanenRobin KaushikAlfie KavalakatJakub KenigVladimir KhokhaDesmond KhorDennis KimJae I. KimVictor KongKonstantinos LasithiotakisPedro LeãoMiguel LeonAndrey LitvinVarut LohsiriwatEudaldo López-Tomassetti FernandezEftychios LostoridisJames MacielPiotr MajorAna DimovaDimitrios ManatakisAthanasio MarinisAleix Martinez-PerezSanjay MarwahMichael McFarlaneCristian MesinaMichał PȩdziwiatrNickos MichalopoulosEvangelos MisiakosAli MohamedahmedRadu MoldovanuGiulia MontoriRaghuveer Mysore NarayanaIonut NegoiIoannis NikolopoulosGiuseppe NovelliViktors NovikovsIyiade OlaoyeLietuvos sveikatos mokslų universitetasHospital de La SerenaRīgas Austrumu klīniskā universitātes slimnīcaBahrain Defence Force Royal Medical ServicesSzpital Uniwersytecki w KrakowieErzincan ÜniversitesiHamad General HospitalUniversity Hospital of the West IndiesThe University of the West IndiesAthens General HospitalBelgrade University School of MedicineOspedale MaggioreUniversità degli Studi di Roma La SapienzaMedical University of PlovdivPt. B.D. Sharma PGIMS, RohtakUniversità Politecnica delle MarcheAretaieion HospitalUniversity of California, San DiegoUniversidade Estadual de CampinasAzienda Ospedaliera San Carlo BorromeoSao Joao HospitalBaskent UniversitesiEdendale HospitalA.H.E.P.A. HospitalUniversity Hospital Birmingham NHS Foundation TrustCentro Hospitalar de Vila Nova de GaiaTurun Yliopistollinen KeskussairaalaHospital Garcia de OrtaKaradeniz Teknik ÜniversitesiHospital Miguel ServetComplejo Hospitalario Universitario Insular Materno-InfantilSakarya ÜniversitesiUniwersytet Jagielloński Collegium MedicumHospital Universitario Fundación Jiménez DíazFundacao Universitaria do ABC, Faculdade de Medicina do ABCHarbor-UCLA Medical CenterOspedale M. BufaliniAttikon University HospitalAristotle University of ThessalonikiUniversità degli Studi di BresciaInje UniversityLarissa General HospitalMansoura UniversityMustafa Kemal ÜniversitesiUniversità degli Studi di Parma, Facoltà di Medicina e ChirurgiaFaculty of Medicine, Siriraj Hospital, Mahidol UniversityAhmadu Bello UniversityUniversity of IlorinLos Angeles County USC Medical CenterHospital Universitario Dr. PesetUniversitätsklinikum Gießen und Marburg, Standort GießenNational Health ServiceUniversity of Zagreb School of MedicineAzienda Sanitaria Ospedaliera Molinette San Giovanni Battista Di TorinoGovernment Medical College & Hospital, ChandigarhSMS Medical CollegeHadassah University Medical CentreHospital Habib Bouguefa de BizerteLandesklinikum HainburgChud-Borgou/AliboriGeneral Hospital George PapanikoalouHospital de BragaYork NHS teaching Hospital TrustSt. Mary ClinicK R Hospital ComplexCity HospitalVladimir City Clinical Hospital of Emergency MedicineEmergency Hospital of BucharestMaternity Hospital Therezinha de JesusJubilee Mission Medical College and Research InstituteAgios Savvas Anticancer HospitalUniversity Clinical Center TuzlaKwara State Specialist HospitalCity Hospital #1Primary Health Care Centre of KissamosSamsun Training and Research HospitalInfermi HospitalAdana Numune Training and Research HospitalRegional HospitalUniversity ClinicCittà di Castello HospitalTzaneio State HospitalKipshidze Central University HospitalKuala Krai HospitalMacerata HospitalRegional Clinical HospitalEmergency Hospital of CraiovaSS Annunziata HospitalKavala General HospitalAzienda Ospedaliera Universitaria Policlinico Paolo GiacconeKhartoum Teaching Hospital2019-08-282019-08-282018-04-16World Journal of Emergency Surgery. Vol.13, No.1 (2018)174979222-s2.0-85045390535https://repository.li.mahidol.ac.th/handle/20.500.14594/46753© 2018 The Author(s). Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments. Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study. Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%. Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.Mahidol UniversityMedicineArticleSCOPUS10.1186/s13017-018-0179-0