Natalia Alencar de PinhoAdeera LevinMasafumi FukagawaWendy E. HoyRoberto Pecoits-FilhoHelmut ReichelBruce RobinsonChagriya KitiyakaraJinwei WangKai Uwe EckardtVivekanand JhaKook Hwan OhLaura SolaSusanne EderMartin de BorstMaarten TaalHarold I. FeldmanBénédicte StengelOgnjenka DjurdjevMila TangNaohiki FujiiShoichi MaruyamaTakahiro ImaizumiJianzhen ZhangZaimin WangHelen G. HealyZiad A. MassyChristian CombeMaurice LavilleRoberto Pecoits FilhoAntonio LopesRonald PisoniBrian BieberCharlotte TuPornpen SangthawanWarangkana PichaiwongPinkaew KlyprayongPaula OrlandiRaymond TownsendAlan GoLuxia ZhangVivek KumarAshok Kumar YadavSeema Baid-AgrawalCurie AhnDong Wan ChaeSeung Hyeok HanPablo G. RiosLiliana GadolaVeronica LamadridJohannes LeiererJulia KerschbaumMartin H. de BorstFrans J. Van IttersumJan A. Van den BrandMaarten A. De JongMaarten W. TaalAdam ShardlowUniversity of QueenslandTokai University School of MedicineUniversity of New South Wales (UNSW) AustraliaCharité – Universitätsmedizin BerlinUniversité Paris-SudPontificia Universidade Catolica do ParanaFaculty of Medicine, Ramathibodi Hospital, Mahidol UniversityUniversity of NottinghamPeking UniversityThe University of British ColumbiaMedizinische Universitat InnsbruckUniversity of Groningen, University Medical Center GroningenUniversity of Pennsylvania Perelman School of MedicineFriedrich-Alexander-Universität Erlangen-NürnbergSeoul National University College of MedicineCentro de Diálisis PeritonealArbor Research Collaborative for HealthNephrological Center2020-01-272020-01-272019-10-01Kidney International. Vol.96, No.4 (2019), 983-99415231755008525382-s2.0-85072224157https://repository.li.mahidol.ac.th/handle/20.500.14594/51407© 2019 International Society of Nephrology Although blood pressure control is a major goal in chronic kidney disease, no worldwide overview of either its achievement or antihypertensive prescriptions is currently available. To evaluate this we compared crude prevalence of uncontrolled blood pressure among 17 cohort studies, including 34 602 individuals with estimated glomerular filtration rate under 60 ml/min/1.73 m2 and treated hypertension across four continents, and estimated observed to expected prevalence ratios, adjusted for potential confounders. Crude prevalence of blood pressure of 140/90 mm Hg or more varied from 28% to 61% and of blood pressure of 130/80 or more from 54% to 84%. Adjusted prevalence ratios indicated poorer hypertension control than expected in cohorts from European countries, India, and Uruguay, and better control in patients from North American and high-income Asian countries. Four antihypertensive drug classes or more were prescribed to more than 30% of participants in North American and some European cohorts, but this practice was less common elsewhere. Renin angiotensin-aldosterone system inhibitors were the most common antihypertensive drugs, prescribed for 54% to 91% of cohort participants. Differences for other drug classes were much stronger, ranging from 11% to 79% for diuretics, 22% to 70% for beta-blockers, and 27% to 75% for calcium-channel blockers. The confounders studied explain only a part of the international variation in blood pressure control among individuals with chronic kidney disease. Thus, considerable heterogeneity in prescription patterns worldwide calls for further investigation into the impact of different approaches on patient outcomes.Mahidol UniversityMedicineArticleSCOPUS10.1016/j.kint.2019.04.032