Robert H. WhiteheadThomas M. YuillDouglas J. GouldPhinit SimasathienArmed Forces Research Institute of Medical Sciences, ThailandMahidol University2018-02-272018-02-271971-01-01Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.65, No.5 (1971), 661-66718783503003592032-s2.0-0015171075https://repository.li.mahidol.ac.th/handle/20.500.14594/8838The susceptibility of two Aedes (Stegomyia) species, Ae. aegypti and Ae. albopictus, to infection with dengue virus was assessed using both natural feeding on a viraemic gibbon and a membrane feeding technique. Both species were highly susceptible to dengue virus infection. It was found that both species were more sensitive than the LLC-MK2 cell plaque assay system used in detecting viraemia in a gibbon infected with a low tissue culture passage strain of dengue-2 virus. However, the same strain passaged in LLC-MK2 cells failed to infect either species when the mosquitoes were fed upon a suspension of this virus. Both species were infected readily when fed upon a suspension of a mouse adapted strain of dengue-2 virus. © 1971 IOP Publishing Ltd.Mahidol UniversityImmunology and MicrobiologyMedicineArticleSCOPUS10.1016/0035-9203(71)90051-4