Boonsirm WithyachumnarnkulPornpimol WongprapairotWantanee TrakulrungsiMahidol University2018-06-142018-06-141987-01-01Journal of Pineal Research. Vol.4, No.2 (1987), 169-1751600079X074230982-s2.0-0023182963https://repository.li.mahidol.ac.th/handle/20.500.14594/15319Dynamics of radioactive accumulation in rat greater salivary glfollowing systemic administration of 3 H‐melatonin was studied to determine a possible action of the hormone in the gland. Progressive decline of 3 H‐melatonin concentrations was found in the serum, lung, skeletal muscle, liver, kidney, salivary glduring 60 min following the administration. On the contrary, there was a progressive accumulation of radioactive substance other than 3 H‐melatonin in the salivary glbut not in other tissues mentioned. The radioactivity was also progressively preferentially localized in the nuclear fraction of the glcells. These results suggest a possible direct action of melatonin derivative in rat salivary gland. Copyright © 1987, Wiley Blackwell. All rights reservedMahidol UniversityBiochemistry, Genetics and Molecular BiologyArticleSCOPUS10.1111/j.1600-079X.1987.tb00853.x