Piyachat ChanselaPorncharn SaitongdeePraphaporn StewartNantawan SoonklangPeter J. HannaPrarinyaporn NuuraiTanes PoomtongPrasert SobhonMahidol UniversityFaculty of Medicine, Thammasat UniversityDeakin UniversityCoastal Aquaculture Research and Development Center2018-09-242018-09-242010-11-01Journal of Shellfish Research. Vol.29, No.3 (2010), 753-756073080002-s2.0-78449306522https://repository.li.mahidol.ac.th/handle/123456789/28440APGW-amide is a well-known neurohormone modulator in several molluscs, and is involved in motor activities, feeding, and sexual behavior. In this report we show that injections of APGW-amide into 4-mo-old juvenile Haliotis asinina stimulate growth of body weight and, to a lesser degree, shell length. The injections were given at 0 (control), 20, and 200 ng/g body weight (BW), at 1-wk intervals for 14 wk. BW and shell length (SL) were measured every week, and growth rates were calculated. When compared with control animals, there was an approximate 2-fold increase in body growth rates of animals given 20 ng/g BW and 200 ng/g BW APGW-amide (P ≤ 0.05), whereas only 20 ng/g BW APGW-amide produced significantly greater SL than controls (P ≤ 0.05), with an approximate 1.2-fold increase. Using an immunoperoxidase technique, we showed the presence of APGW-amide in neuronal cells of the cerebral ganglia and nerve fibers. Overall, these data indicate that APGW-amide is an important neurohormone/neuromodulator in the nervous system of H. asinina and plays a role in controlling the body growth of H. asinina. .Mahidol UniversityAgricultural and Biological SciencesThe tetrapeptide apgw-amide induces somatic growth in haliotis asinina linnaeusConference PaperSCOPUS10.2983/035.029.0329