Samarium(II) iodide-mediated deoxygenative debromination of α-bromo-β-hydroxy (acetoxy) phenyl sulfones: Synthesis of α,β-unsaturated sulfones

Vichai ReutrakulSuwatchai JarussophonManat PohmakotrYupa ChaiyasutSaengvimon U-ThetPatoomratana TuchindaMahidol University2018-07-242018-07-242002-03-18Tetrahedron Letters. Vol.43, No.12 (2002), 2285-2288004040392-s2.0-0037128515https://repository.li.mahidol.ac.th/handle/20.500.14594/20073Deoxygenative debromination of α-bromo-β-hydroxy (acetoxy) phenyl sulfones with samarium(II) iodide led to substituted α,β-unsaturated sulfones in good to excellent yields. The E-isomer is the major product. A possible mechanism via an α-sulfonyl radical pathway is proposed. © 2002 Elsevier Science Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsSamarium(II) iodide-mediated deoxygenative debromination of α-bromo-β-hydroxy (acetoxy) phenyl sulfones: Synthesis of α,β-unsaturated sulfonesArticleSCOPUS10.1016/S0040-4039(02)00224-1