Ekasith SomsookDuangduean HinsinPasakorn BuakhrongRattapon TeanchaiNattinee MophanManat PohmakotrJuwadee ShiowatanaMahidol University2018-06-212018-06-212005-08-29Carbohydrate Polymers. Vol.61, No.3 (2005), 281-287014486172-s2.0-24144463771https://repository.li.mahidol.ac.th/handle/20.500.14594/16201This paper is aimed to study the nature of iron(III)-saccharide interactions in complexes and to look for new iron-containing drugs for supplementing organisms. Iron(III)-saccharide complexes were synthesized by reacting FeCl3and saccharides (rice starch, sucrose, and dextran) in basic solutions and their characteristics were compared with synthetic iron-oxide. Both crystalline and amorphous iron(III) complexes were obtained and identified by X-ray diffraction (XRD). Amorphous samples were chosen to investigate the interactions between iron(III) and saccharides by continuous-flow dissolution experiments. In acidic solution, the rate of iron release from amorphous iron complexes increased with the following order: iron-rice starch≈iron-oxide≪iron-sucrose≈iron-dextran. The colloidal structure of iron-rice starch was proposed to describe its similar dissolution profile with that of iron-oxide. © 2005 Elsevier Ltd. All rights reserved.Mahidol UniversityAgricultural and Biological SciencesBiochemistry, Genetics and Molecular BiologyArticleSCOPUS10.1016/j.carbpol.2005.04.019