Natakarn NimsanorIda JørringMikkel A. RasmussenChristian ClausenUlrike A. Mau-HolzmannNarisorn KitiyanantJørgen E. NielsenTroels T. NielsenPoul HyttelBjørn HolstBenjamin SchmidBioneer ASKøbenhavns UniversitetUniversität TübingenMahidol University2018-12-112019-03-142018-12-112019-03-142016-11-01Stem Cell Research. Vol.17, No.3 (2016), 564-56718767753187350612-s2.0-85028080077https://repository.li.mahidol.ac.th/handle/20.500.14594/42863© 2016 Michael Boutros, German Cancer Research Center, Heidelberg, Germany Frontotemporal dementia with parkinsonism linked to chromosome 17q21.2 (FTDP-17) is an autosomal-dominant neurodegenerative disorder. Mutations in the gene coding the microtubule-associated protein tau (MAPT) can cause FTDP-17 but the underlying mechanisms of the disease are still unknown. Induced pluripotent stem cells (iPSCs) hold great promise to model FTDP-17 as such cells can be differentiated in vitro to the required neuronal cell type. Here, we report the generation of iPSCs from a 44-year-old symptomatic woman carrying a S305I mutation in the MAPT-gene.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyArticleSCOPUS10.1016/j.scr.2016.10.006