Samreang BunteangWaraporn ChanakulSakchai HongthongChutima KuhakarnWatcharra ChintakovidNatthapat SungchawekRadeekorn AkkarawongsapatJitra LimthongkulNarong NantasaenVichai ReutrakulThaworn JaipetchKing Mongkut's University of Technology North BangkokMahidol UniversityMinistry of Natural Resources and Environment2019-08-232019-08-232018-01-01Natural Product Communications. Vol.13, No.1 (2018), 29-32155594751934578X2-s2.0-85048478142https://repository.li.mahidol.ac.th/handle/123456789/44888© 2018 Natural Product Incorporation. All Rights Reserved. Bioassay-guided fractionation of the aerial parts of Dasymaschalon echinatum led to the isolation of five known aristolactams; aristolactam AII (1), aristolactam BII (2), piperolactam A (3), piperolactam C (4), and goniopedaline (5), together with two aphorphine alkaloids; duguevalline (6) and noraristolodione (7) and two amide derivatives; asperphenamate (8), and N-benzoyl-L-phenylalaninol (9). Alkaloids 2 and 7 were isolated for the first time from the Dasymaschalon genus. The anti-HIV 1 reverse transcriptase (RT) activity of all isolated compounds was determined. Except for aristolactam BII (2), this is the first report of the anti-HIV 1-RT activity of compounds 1 and 3-9. Compounds 1, 3, 5, 6 and 8 showed weak anti-HIV 1-RT inhibitory activity with IC50 ranging from 112.74 to 225.55 M.Mahidol UniversityAgricultural and Biological SciencesMedicinePharmacology, Toxicology and PharmaceuticsArticleSCOPUS