Chaisrisawadisuk S.Khampalikit I.Chankaew E.Moore M.H.Mahidol University2024-02-152024-02-152024-01-01Child's Nervous System (2024)02567040https://repository.li.mahidol.ac.th/handle/20.500.14594/97183Cloverleaf skull deformity or Kleeblattschadel syndrome is a severe condition where multiple cranial sutures are absent and prematurely fused, leading to a trilobate head shape. The remaining open sutures or fontanelles compensate for rapid brain expansion, while the constricted fused calvarium restricts brain growth and results in increased intracranial pressure. Recent data show that early posterior cranial and foramen magnum decompression positively affects infants with cloverleaf skulls. However, long-term sequelae are still rarely discussed. We hereby report a child who developed secondary metopic craniosynostosis after posterior cranial decompression, which required a front-orbital advancement and cranial remodelling as a definitive procedure.MedicineArticleSCOPUS10.1007/s00381-024-06309-82-s2.0-8518416412314330350