Buitendag J.Variawa S.Diayar A.Snyders P.Rademan P.Allopi N.McGreevy D.T.Hörer T.M.Oosthuizen G.Sadeghi M.Pirouzram A.Toivola A.Larzon T.Nilsson K.F.Skoog P.Idoguchi K.Kon Y.Ishida T.Matsumura Y.Matsumoto J.Reva V.Maszkowski M.Bersztel A.Caragounis E.C.Falkenberg M.Handolin L.Abu-Zidan F.M.Szarka E.Manchev V.Wannatoop T.Chang S.W.Kessel B.Hebron D.Shaked G.Bala M.Coccolini F.Ansaloni L.Ordoñez C.A.Dogan E.M.Manning J.E.Hibert-Carius P.Mahidol University2024-02-082024-02-082023-07-11Journal of Endovascular Resuscitation and Trauma Management Vol.7 No.1 (2023) , 8-1420027567https://repository.li.mahidol.ac.th/handle/123456789/95578Background: Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) is a helpful adjunct in the management of hemorrhagic shock due to bleeding in the abdomen or pelvis. Ischemia distal to the occlusion is a concern; intermittent aortic balloon inflation (i-REBOA) is a novel way to achieve decreased ischemia time. Methods: This study was conducted using data from the multinational ABO Trauma Registry. All patients entered between January 2016 and December 2019 were included. Results: The sample consisted of 157 patients. There were 57 patients in the i-REBOA group (36%) and 100 in the REBOA group (64%). The groups were similar in gender (P = 0.50), age (P = 0.17), mechanism of injury (P = 0.42), and injury severity score (P = 0.13). The levels of international normalized ratio (INR) (P < 0.01), activated partial thromboplastin time (aPTT) (P < 0.01) and lactate (P = 0.02) were higher in the i-REBOA group. Total balloon inflation times were longer in the i-REBOA group (P < 0.01). Major complication rates did not differ between groups. Mortality rates between groups were similar in the Emergency Department (ED) (3.8% for i-REBOA vs 10.1%; P = 0.17), within 24 hours (43.4% for i-REBOA vs 38.2%; P = 0.54), and at 30 days (63.6% for i-REBOA vs 48.4%; P = 0.07). Conclusions: The data from this registry show that i-REBOA is currently being used and may allow for longer total balloon inflation times without higher morbidity or mortality ratesMedicineArticleSCOPUS10.26676/jevtm.2752-s2.0-851802284932003539X