Nongpanga NingsanontDavid St C BlackRachada ChanphenYodhathai ThebtaranonthMahidol UniversityUniversity of New South Wales (UNSW) AustraliaThailand National Center for Genetic Engineering and Biotechnology2018-07-242018-07-242003-06-05Journal of Medicinal Chemistry. Vol.46, No.12 (2003), 2397-2403002226232-s2.0-0038101387https://repository.li.mahidol.ac.th/handle/20.500.14594/20720Derivatives of ethyl 5-phenyl-6-oxa-1-azabicyclo[3.1.0]hexane-2-carboxylate (14-20), with side chains varying from three to five carbon atoms and bearing various substituents, have been prepared from ethyl 2-phenyl-1-pyrroline-5-carboxylate (12). Their in vitro activity against P. falciparum (K1 strain) and antimycobacterium and also their cytotoxic activity against Vero cell have been evaluated.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1021/jm020452h