Onnicha KhaikateJatuporn MeesinManat PohmakotrVichai ReutrakulPawaret LeowanawatDarunee SoorukramChutima KuhakarnMahidol University2019-08-232019-08-232018-01-01Organic and Biomolecular Chemistry. Vol.16, No.44 (2018), 8553-8558147705202-s2.0-85056520766https://repository.li.mahidol.ac.th/handle/20.500.14594/45272© The Royal Society of Chemistry. Diverse 2-sulfonyl- and 2-thiocyanato-3-substituted quinolines were synthesized from o-alkynylisocyanobenzenes by nucleophilic addition of the respective sulfinate sodium salts and ammonium thiocyanate to the isocyanide moiety followed by cyclization. The salient features of the methodology include metal-free, ambient temperature and mild reaction conditions, ease of reagent handling, and broad functional group tolerance.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistrySulfinates and thiocyanates triggered 6-endo cyclization of o-alkynylisocyanobenzenesArticleSCOPUS10.1039/C8OB02338G