Ching Ju ChiuYung Chen YuYe Fong DuYi Ching YangJou Yin ChenLi Ping WongChanuantong TanasugarnNational Cheng Kung University HospitalUniversity of MalayaNational Cheng Kung UniversityMahidol University2020-08-252020-08-252020-01-01JMIR mHealth and uHealth. Vol.8, No.6 (2020)229152222-s2.0-85085904615https://repository.li.mahidol.ac.th/handle/20.500.14594/58307© 2020 Ching-Ju Chiu, Yung-Chen Yu, Ye-Fong Du, Yi-Ching Yang, Jou-Yin Chen, Li-Ping Wong, Chanuantong Tanasugarn. Background: Many technology-assisted innovations have been used to manage disease. However, most of these innovations are not broadly used by older adults due to their cost. Additionally, disease management through technology-assisted innovations has not been compared with other interventions. Objective: In this study, we tested the employment of a free and widely used social and communication app to help older adults with diabetes manage their distress and glycemic control. We also compared the effectiveness of the app with 2 other methods, namely telephone and conventional health education, and determined which subgroup experiences the most effects within each intervention. Methods: Adults aged ≥50 years with type 2 diabetes were recruited from Southern Taiwan (N=231) and were allocated to different 3-month interventions. Informed consent was obtained at the Ministry of Science and Technology and approved by the National Cheng Kung University Hospital Institutional Review Board (No. A-ER-102-425). Results: Participants in the mobile-based group had significant reductions in hemoglobin A1c compared with the telephone-based and usual care groups (mean changes of -0.4%, 0.1%, and 0.03%, respectively; P=.02). Diabetes-specific distress decreased to a greater extent in the mobile-based group compared to the other 2 groups (mean changes of -5.16, -3.49, and -2.44, respectively, P=.02). Subgroup analyses further revealed that the effects on reducing blood glucose levels in the social and communication app groups were especially evident in patients with lower distress scores, and diabetes-related distress was especially evident in participants who were younger than 60 years or had higher educational levels. Conclusions: The findings of this study inform more flexible use of social and communication apps with in-person diabetes education and counselling.Mahidol UniversityMedicineArticleSCOPUS10.2196/14024