Yatida WuttisartkulRungson ChomeyaWirin KittipichaiMahasarakham UniversityMahidol University2018-11-232018-11-232015-05-15Asian Social Science. Vol.11, No.15 (2015), 146-15019112025191120172-s2.0-84930635763https://repository.li.mahidol.ac.th/handle/123456789/35305© 2015 Canadian Center of Science and Education. All rights reserved. The purposes of this study were to (1) study and develop the measurement of 5 minds for 21st century, (2) develop the 5 components of minds, (3) develop the 5 minds development program, (4) compare the scorings from the measurement of 5 minds for 21st century before and after participating in intervention, and (5) study the effectiveness of the mind developed program. Participants were 333 nurse students; of those, 32 students were included in the experiment group. Simple random sampling was used to assign students into two groups. Instruments were the 5 minds for 21st century scale, and psychological group training the 5 minds for 21^st century program. Data was analyzed by using Confirmatory Factor Analysis, Wilcoxon Match Pair Signed Ranks Test, and Mann Whitney U Test, respectively. The measurement of 5 minds for 21^st century included 70 items with the Likert scale ratings, and the Cronbach’s Alpha was .935. The confirmatory factor analysis showed statistic significant difference in five components of minds, and these were integrated in to 12 activities of psychological group training-5 minds for 21st century program. The researcher found that psychological group training could be used to develop 5 minds because this program showed the effectiveness at an adequate level. Study showed statistically significant differences in the mean scores of minds in the experimental group between before and after participating in the program, except the Respectful mind component.Mahidol UniversityArts and HumanitiesEconomics, Econometrics and FinanceArticleSCOPUS10.5539/ass.v11n15p146