T. GlinsukonC. ToskulkaoP. PiyachaturawatMahidol University2018-10-122018-10-121982-12-01Research Communications in Chemical Pathology and Pharmacology. Vol.38, No.2 (1982), 247-251003451642-s2.0-0020383823https://repository.li.mahidol.ac.th/handle/123456789/30411The inhibitory effect of cytochalasin E on galactose absorption in everted sacs of mouse jejunum was studied. Cytochalasin B had highest potency on the inhibition of galactose absorption when it was added in the mucosal solution followed by cytochalasins E, A, C and D respectively. Cytochalasin E at a concentration as low as 2.5 μg/ml could inhibit galactose absorption by 17.1% within 60 min incubation and its maximum inhibition was obtained at a concentration of 10.0 μg/ml. At this concentration, it inhibited both Na+-dependent and independent galactose absorption. Our results in the present study and previously reported indicate that cytochalasin E inhibits the active intestinal absorption of galactose as well as glucose in the mouse.Mahidol UniversityPharmacology, Toxicology and PharmaceuticsArticleSCOPUS