Charoenlerdchanya A.Keangin P.Mahidol University2024-06-032024-06-032024-05-17AIP Conference Proceedings Vol.3086 No.1 (2024)0094243Xhttps://repository.li.mahidol.ac.th/handle/20.500.14594/98618Currently, cancer is the second-leading cause of death worldwide. The wide variety of methods for treating cancer includes surgery, radiation therapy, and chemotherapy. All of these methods have adverse effects on the patient. Thermal ablation from microwave energy, also known as microwave ablation, is one of the more popular methods with fewer side effects. Effective cancer treatments need to destroy as many cancer cells as possible. In other words, they reduce cancer cell viability. From previous research, cell viability should be less than 50%. However, it is still difficult to experiment with microwave ablation treatment for cancer cells. Non-cancer cells cultured via in vitro techniques are another option for experimental studies during microwave ablation. In this research, the cell viability of connective tissue (L929) by microwave ablation for cells cultured during in vitro experiments is studied. There are two parameters in this study: microwave antenna slots (single, double, and triple slots) and microwave power (5 W, 10 W, and 20 W) over 10 min. The results show that the single-slot microwave antenna and power of 5 W have less effect on the cultured cells. There are two cases of single-slot microwave antenna with 5 W and 10 W, with cell viability above 50% (87.31% and 69.64%, respectively). From the double slot of a microwave antenna, only one case of 5 W has cell viability of more than 50% (87.21%), and one case of 5 W using a triple slot has cell viability of more than 50% (86.50%). The study will increase knowledge of the effects of microwave ablation methods on biological cells at the cellular level.Physics and AstronomyConference PaperSCOPUS10.1063/5.02107932-s2.0-8519441189015517616