Berthold KoletzkoChristopher C.M. BoeyCristina CampoySusan E. CarlsonNamsoo ChangMaria Antonia Guillermo-TuazonSadhana JoshiChristine PrellSeng Hock QuakDamayanti Rusli SjarifYixiang SuSarayut SupapannachartYuichiro YamashiroSaskia J.M. OsendarpKlinikum der Universitat MunchenUniversity of MalayaUniversidad de GranadaUniversity of Kansas Medical CenterEwha Womans UniversityUniversity of the Philippines Los BanosBharati Vidyapeeth UniversityNational University Hospital, SingaporeUniversity of Indonesia, RSUPN Dr. Cipto MangunkusumoMahidol UniversityJuntendo University School of MedicineOsendarp NutritionThe Micronutrient InitiativeSun Yat-Sen University2018-11-092018-11-092014-01-01Annals of Nutrition and Metabolism. Vol.65, No.1 (2014), 49-8014219697025068072-s2.0-84908562442https://repository.li.mahidol.ac.th/handle/123456789/34873© 2014 S. Karger AG, Basel. The Early Nutrition Academy supported a systematic review of human studies on the roles of pre- and postnatal longchain polyunsaturated fatty acids (LC-PUFA) published from 2008 to 2013 and an expert workshop that reviewed the information and developed recommendations, considering particularly Asian populations. An increased supply of n-3 LC-PUFA during pregnancy reduces the risk of preterm birth before 34 weeks of gestation. Pregnant women should achieve an additional supply ≥ 200 mg docosahexaenic acid (DHA)/day, usually achieving a total intake ≥ 300 mg DHA/day. Higher intakes (600-800 mg DHA/day) may provide greater protection against early preterm birth. Some studies indicate beneficial effects of pre- and postnatal DHA supply on child neurodevelopment and allergy risk. Breast-feeding is the best choice for infants. Breast-feeding women should get ≥ 200 mg DHA/day to achieve a human milk DHA content of ∼ 0.3% fatty acids. Infant formula for term infants should contain DHA and arachidonic acid (AA) to provide 100 mg DHA/day and 140 mg AA/day. A supply of 100 mg DHA/day should continue during the second half of infancy. We do not provide quantitative advice on AA levels in follow-on formula fed after the introduction of complimentary feeding due to a lack of sufficient data and considerable variation in the AA amounts provided by complimentary foods. Reasonable intakes for very-low-birth weight infants are 18-60 mg/ kg/day DHA and 18-45 mg/kg/day AA, while higher intakes (55-60 mg/kg/day DHA, ∼ 1% fatty acids; 35-45 mg/kg/day AA, ∼0.6-0.75%) appear preferable. Research on the requirements and effects of LC-PUFA during pregnancy, lactation, and early childhood should continue.Mahidol UniversityMedicineNursingArticleSCOPUS10.1159/000365767