M. A. PfallerD. J. DiekemaA. L. ColomboC. KibblerK. P. NgD. L. GibbsV. A. NewellJorge FinquelievichNora TiraboschiDavid EllisDominique FramereeAnnemarie van den AbeeleJean Marc SenterreArnaldo ColomboRobert RennieSteve SancheBijie HuYingchun XuYingyuan ZhangNan Shan ZhongPilar RivasAngela RestrepoCatalina BedoutRicardo VegaMatilde MendezNada MallatovaStanislava DobiasovaJulio AyabacaJeannete ZuritaM. MallieE. CandolfiW. FegelerA. HaaseG. RodloffW. BarV. CzaikaGeorge PetrikosErzsébet PuskásIlona DocziMestyan GyulaRadka NikolovaUma BanerjeeNathan KellerVivian TullioGian Carlo SchitoGiacomo FortinaGian Piero TestoreDomenico D'AntonioGiorgio ScalisePietro MartinoGraziana MannoKee PengCelia AlpucheJose SantosEduardo Rodriguez NoriegaMussaret ZaidiJacques F.G.M. MeisEgil LingaasDanuta DzierzanowskaWaclaw PawliszynMariada Luz MartinsLuis AlbuquerqueLaura RosadoRosa VelhoJose AmorimVera N. IlinaOlga I. KretchikovaGalina A. KlyasovaSophia M. RozanovaIrina G. MultykhNikolay N. KlimkoElena D. AgapovaNatalya V. DmitrievaAbdul Mohsen Al-RasheedJan TruplLeon LangsadlAlena VaculikovaHupkova HelenaDenise RoditiAnwar HoosenH. H. Crewe-BrownM. N. Janse van RensburgAdriano DuseKyungwon LeeMi Na KimA. del PalacioAurora Sanchez-SousaJacques BilleK. MuhlethalerShan Chwen ChangJen Hsien WangMalai VorachitDeniz GurVolkan KortenJohn PaulBrian JonesF. Kate GouldChris KibblerNigel WeightmanIan M. GouldUniversity of Iowa Carver College of MedicineUniversidade Federal de Sao PauloUCLUniversity of MalayaGiles Scientific, Inc.Universidad de Buenos AiresHospital Escuela Gral.Women's and Children's Hospital AdelaideCHU de JumetSt. Lucas Campus Heilige FamilieCentre Hospitalier Regional de La CitadelleUniversity of Alberta HospitalRoyal University HospitalZhongshan Hospital ShanghaiPeking Union Medical CollegeHuashan HospitalGuangzhou Institute of Repiratory DiseaseUniversidad Nacional de ColombiaCIBHospital Militar Central, BogotaHospital Ceske BudejoviceHospital FF. AA HG1Hospital VozandesInstitut de ParasitologieWestfalische Wilhelms-Universitat MunsterRheinisch-Westfalische Technische Hochschule AachenInst. F. Med. MikrobiologieCarl-Thiem-KlinikumHumaine KlinikenLaikon General HospitalBAZ County InstituteSzegedi Tudomanyegyetem (SZTE)Pecsi TudomanyegyetemSzent Laszlo HospitalAll India Institute of Medical Sciences, New DelhiChaim Sheba Medical Center IsraelUniversita degli Studi di TorinoUniversita degli Studi di GenovaOspedale di NovaraUniversita degli Studi di Roma Tor VergataOspedale Civile di PescaraInstituto di Malattie InfettiveHospital General de MexicoUniversidad de GuadalajaraHospital General O'HoranNijmegen Interdenominational Hospital Canisius-WilhelminaRikshospitalet-Radiumhospitalet HFInstytut Pomnik-Centrum Zdrowia DzieckaPracownia BakteriologiiUniversidade Nova de Lisboa, Instituto de Higiene e Medicina TropicalCentro Hospitalar e Universitario de CoimbraInstituto Nacional de Saude Dr. Ricardo JorgeHospital Geral de Santo AntonioNovosibirsk Regional HospitalNorth-Western State Medical University named after I.I. MechnikovNational Research Center for HematologyCity Clinical Hospital No.Territory Center of Laboratory DiagnosticsMedical Mycology Research InstituteIrkutsk Regional Childrens HospitalOncology Research CenterRiyadh Military HospitalNational Cancer CenterDerer's University Hospital SlovakiaSt. Cyril and Method HospitalGroote Schuur HospitalSefako Makgatho Health Sciences University (SMU)Baragwanath HospitalUniversity of the Free StateJohannesburg HospitalYonsei University College of MedicineAsan Medical CenterHospital 12 De OctobreHospital Ramon y CajalCentre Hospitalier Universitaire VaudoisUniversitat BernNational Taiwan University HospitalChina Medical University Hospital TaichungMahidol UniversityHacettepe Children's HospitalMarmara Universitesi Tip FakultesiRoyal Sussex County HospitalGlasgow Royal InfirmaryFreeman HospitalFriarage HospitalAberdeen Royal InfirmaryLeeds General InfirmaryCardiff UniversityWayne State UniversityThe Mount Sinai Medical CenterWeill Cornell Medical CenterStanford University Medical CenterUniversity Hospitals Case Medical CenterUniversity of Texas Health Science Center at San AntonioUniversity of VirginiaChristiana Care2018-08-202018-08-202006-10-01Journal of Clinical Microbiology. Vol.44, No.10 (2006), 3578-3582009511372-s2.0-33947634712https://repository.li.mahidol.ac.th/handle/123456789/23594Candida rugosa is a fungus that appears to be emerging as a cause of infection in some geographic regions. We utilized the extensive database of the ARTEMIS DISK Antifungal Surveillance Program to describe the geographic and temporal trends in the isolation of C. rugosa from clinical specimens and the in vitro susceptibilities of 452 isolates to fluconazole and voriconazole. C. rugosa accounted for 0.4% of 134,715 isolates of Candida, and the frequency of isolation increased from 0.03% to 0.4% over the 6.5-year study period (1997 to 2003). C. rugosa was most common in the Latin American region (2.7% versus 0.1 to 0.4%). Decreased susceptibility to fluconazole (40.5% susceptible) was observed in all geographic regions; however, isolates from Europe and North America were much more susceptible (97 to 100%) to voriconazole than those from other geographic regions (55.8 to 58.8%). C. rugosa was most often isolated from blood and urine in patients hospitalized at the Medical and Surgical inpatient services. Notably, bloodstream isolates were the least susceptible to both fluconazole and voriconazole. C. rugosa should be considered, along with the established pathogens Candida krusei and Candida glabrata, as a species of Candida with reduced susceptibility to the azole antifungal agents. Copyright © 2006, American Society for Microbiology. All Rights Reserved.Mahidol UniversityMedicineArticleSCOPUS10.1128/JCM.00863-06