Praphan PhanuphakSunee SirivichayakulAwachana JiamsakulSomnuek SungkanuparphNagalingeswaran KumarasamyMan Po LeeThira SirisanthanaPacharee KantipongChristopher LeeAdeeba KamarulzamanMahiran MustafaRossana DitangcoTuti MeratiWinai RatanasuwanThida SingtorojRami KantorThe HIV Netherlands Australia Thailand Research CollaborationChulalongkorn UniversityUniversity of New South Wales (UNSW) AustraliaMahidol UniversityYR Gaitonde Centre for AIDS Research and EducationQueen Elizabeth Hospital Hong KongChiang Mai UniversityChiangrai Prachanukroh HospitalHospital Sungai BulohUniversity of MalayaHospital Raja Perempuan Zainab IIGokilaUniversitas UdayanaamfAR - The Foundation for AIDS ResearchBrown University2018-11-092018-11-092014-05-01Journal of Acquired Immune Deficiency Syndromes. Vol.66, No.1 (2014), 74-7910779450152541352-s2.0-84898539282https://repository.li.mahidol.ac.th/handle/20.500.14594/34249BACKGROUND: We compared treatment outcomes of transmitted drug resistance (TDR) in patients on fully or partially sensitive drug regimens. METHODS: Factors associated with survival and failure were analyzed using Cox proportional hazards and discrete time conditional logistic models. RESULTS: TDR, found in 60 (4.1%) of 1471 Asian treatment-naive patients, was one of the significant predictors of failure. Patients with TDR to >1 drug in their regimen were >3 times as likely to fail compared to no TDR. CONCLUSIONS: TDR was associated with failure in the context of non-fully sensitive regimens. Efforts are needed to incorporate resistance testing into national treatment programs. © 2013 by Lippincott Williams and Wilkins.Mahidol UniversityMedicineArticleSCOPUS10.1097/QAI.0000000000000108