S. TharavanijMahidol University2018-10-122018-10-121985-12-01Southeast Asian Journal of Tropical Medicine and Public Health. Vol.16, No.2 (1985), 314-331003836192-s2.0-0022397892https://repository.li.mahidol.ac.th/handle/20.500.14594/30805This review has focused in 3 areas of rapidly developing fields of malaria immunology comprising specific and non-specific immune mechanisms, parasite evasion mechanism and vaccine development. Clear understanding of the host immune mechanisms as well as the parasite evasion mechanisms will help in planning a strategy for the future control of malaria. Rapid progress has been made in the study on host-parasite relationship and identification of 'candidate' antigens for use as the vaccine. Through recombinant DNA technology and synthesis of immunodominant 'protective' peptides, there is hope for malaria vaccine in the near future. The ideal vaccine should be multivalent directed against sporozoites, blood stages and gametes.Mahidol UniversityMedicineArticleSCOPUS