Dominique LaurentFrancine BaumannAnne Gaelle BenoitAlain MortelecqeNarong NitatpattanaIsabelle DesvignesCécile DebitusManola LailleJean Paul GonzalezEliane ChungueInstitut de Recherche pour le Developpement NoumeaInstitut Pasteur de Nouvelle-Caledonie NoumeaMahidol UniversityUniversite de la Nouvelle-CaledonieUniversite Paul Sabatier Toulouse III2018-06-212018-06-212005-07-01Southeast Asian Journal of Tropical Medicine and Public Health. Vol.36, No.4 (2005), 901-905012515622-s2.0-27744551966https://repository.li.mahidol.ac.th/handle/20.500.14594/16939The virucidal and antiviral photoactivities of three compounds, hypericin, tetrabromohypericin and gymnochrome B, were evaluated against dengue viruses. All the three products were active, and both the virucidal and antiviral activities were enhanced by light. Gymnochrome B was more potent than hypericin and tetrabromohypericin. The presence of the side chains on the hypericin core of gymnochromes appears to be beneficial for both virucidal and antiviral activities. This enhanced activity is likely to be linked to a complementary mechanism independent of photoactivation.Mahidol UniversityMedicineArticleSCOPUS