Manee RattanachaiyanontKitirat TechatraisakPhaibul JitpraphaiPhakphum PhophongPichai CharoenpanichMahidol University2018-09-072018-09-071999-05-01Journal of the Medical Association of Thailand. Vol.82, No.5 (1999), 505-509012522082-s2.0-0043080341https://repository.li.mahidol.ac.th/handle/20.500.14594/25652A case of testicular regression syndrome was reported. The patient was an 18 year old girl presenting with primary amenorrhoea. Physical examination revealed normal female external genitalia and underdeveloped secondary sexual characteristics. Hormonal profile indicated gonadal failure. Chromosome analysis revealed 46,XY karyotype. Diagnostic laparoscopy demomstrated undeveloped internal genital organs. Remnants of epididymis, vas deferens and seminiferous tubule were uncovered during exploratory laparotomy. Ontogeny of sexual differentiation and pathogenesis of testicular regression syndrome were reviewed and discussed.Mahidol UniversityMedicineArticleSCOPUS