Maneechotesuwan K.Juthong S.Sangsayunh P.Ratanawatkul P.Vathesatogkit P.Yingchoncharoen T.Chirakarnjanakorn S.Wong C.K.Sriprasart T.Mahidol University2026-04-292026-04-292026-01-01International Journal of Copd Vol.21 (2026)11769106https://repository.li.mahidol.ac.th/handle/123456789/116443Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide and results in chronic lung damage and airway obstruction, significantly impacting individual health. Apart from increased all-cause mortality, COPD exacerbations are associated with higher rates of cardiovascular (CV) events—driven by shared risk factors and pathophysiological mechanisms—with peaks in the first 30 days of post-exacerbation. Therefore, cardiopulmonary risk management is essential during this vulnerable period. This narrative review was developed through an evaluation of clinical studies, guideline recommendations and Thailand-specific data to outline cardiopulmonary linkage in COPD and propose post-COPD exacerbation management. Patient management strategies include optimized pharmacological and non-pharmacological therapies, integrated cardiopulmonary care and CV risk assessment to reduce exacerbations, mortality and CV-related events, particularly in COPD patients with established or suspected CV diseases. Furthermore, implementation of these concepts should emphasize strengthening multidisciplinary awareness among pulmonary and cardiology through professional education, continuing-development activities and integration of collaborative care into national guidelines.MedicineReviewSCOPUS10.2147/COPD.S5919992-s2.0-10503629211611782005