Peerapat ThaisiamPinyo RattanaumpawanMahidol University2018-11-092018-11-092014-01-01Journal of the Medical Association of Thailand. Vol.97, No.12 (2014), 1364-136901252208012522082-s2.0-84924333023https://repository.li.mahidol.ac.th/handle/20.500.14594/34406© 2014, Medical Association of Thailand. All rights reserved. We report a case of endogenous endophthalmitis and endocarditis caused by a rare causative organism: Streptococcus pneumoniae. A 69-year-old woman with diabetes mellitus and pre-existing mitral regurgitation presented with acute fever and severe left eye pain. Ophthalmologic examination revealed bilateral endophthalmitis. Blood and vitreous fluid culture grew penicillin-susceptible S. pneumoniae. Transesophageal echocardiogram documented a 5-mm oscillating mass at right coronary cusp of aortic valve. After 4 weeks of combined ceftriaxone and levofloxacin therapy, the patient improved and was later discharged with blindness in her left eye.Mahidol UniversityMedicineRare manifestations of Streptococcus pneumonia infection; the first case report in Thailand and literature review of pneumococcal endophthalmitis and endocarditisArticleSCOPUS