Direct oral anticoagulants in asian patients with atrial fibrillation: Consensus recommendations by the Asian Pacific Society of Cardiology on strategies for thrombotic and bleeding risk management

Daniel T.T. ChongFelicita AndreottiPeter VerhammeJamshed J. DalalNoppacharn UaprasertChun Chieh WangYoung Keun OnYi Heng LiJun JiangKoji HasegawaKhalid AlmutiRong BaiSidney T.H. LoRungroj KrittayaphongLai Heng LeeDavid K.L. QuekSofian JoharSwee Chong SeowChristopher J. HammettJack W.C. TanSiriraj HospitalNational Hospital Organization Kyoto Medical CenterCleveland Clinic Abu DhabiFondazione Policlinico Universitario Agostino Gemelli IRCCSBeijing Anzhen Hospital, Capital Medical UniversityChang Gung University College of MedicineRaja Isteri Pengiran Anak Saleha HospitalNational University HospitalZhejiang University School of MedicineRoyal Brisbane and Women's HospitalChulalongkorn UniversityKU LeuvenSingapore General HospitalSKKU School of MedicinePantai Holdings Sdn BhdNational Heart Centre, SingaporeNational Cheng King University HospitalSengkang General HospitalKokilaben HospitalLiverpool Hospital2022-08-042022-08-042021-01-01European Cardiology Review. Vol.16, (2021)17583764175837562-s2.0-85108117546https://repository.li.mahidol.ac.th/handle/20.500.14594/78702The disease burden of AF is greater in Asia-Pacific than other areas of the world. Direct oral anticoagulants (DOACs) have emerged as effective alternatives to vitamin K antagonists (VKA) for preventing thromboembolic events in patients with AF. The Asian Pacific Society of Cardiology developed this consensus statement to guide physicians in the management of AF in Asian populations. Statements were developed by an expert consensus panel who reviewed the available data from patients in Asia-Pacific. Consensus statements were developed then put to an online vote. The resulting 17 statements provide guidance on the assessment of stroke risk of AF patients in the region, the appropriate use of DOACs in these patients, as well as the concomitant use of DOACs and antiplatelets, and the transition to DOACs from VKAs and vice versa. The periprocedural management of patients on DOAC therapy and the management of patients with bleeding while on DOACs are also discussed.Mahidol UniversityMedicineDirect oral anticoagulants in asian patients with atrial fibrillation: Consensus recommendations by the Asian Pacific Society of Cardiology on strategies for thrombotic and bleeding risk managementArticleSCOPUS10.15420/ECR.2020.43