Sakchai HongthongJatuporn MeesinPhanruethai PaileeDarunee SoorukramPalangpon KongsaereeSamran PrabpaiPawinee PiyachaturawatSurawat JariyawatKanoknetr SuksenThaworn JaipetchNarong NuntasaenVichai ReutrakulChutima KuhakarnMahidol UniversityChulabhorn Research InstituteNational Park, Wildlife and Plant Conservation Department, Thailand2018-12-112019-03-142018-12-112019-03-142016-01-01Bioorganic and Medicinal Chemistry Letters. Vol.26, No.23 (2016), 5773-5779146434050960894X2-s2.0-84996527546https://repository.li.mahidol.ac.th/handle/20.500.14594/43317© 2016 Elsevier Ltd Five new lanostanes, wallichinanes A–E (1–5) together with a known lanostane derivative 6 were isolated from the cytotoxic hexanes extract of fruits of Garcinia wallichii Choisy (Guttiferae). The structures of the isolated compounds were established by analysis of spectroscopic data, X-ray diffraction technique as well as comparison with the literature data. The cytotoxicity of all isolated compounds against a panel of cultured cancer cell lines was evaluated. Compound 4 exhibited good cytotoxicity with ED50values ranging from 3.91 to 7.63 μM.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryArticleSCOPUS10.1016/j.bmcl.2016.10.045