Saw Thu WahHathairad HananantachaiUsanee KerdpinChotiros PlabpluengVirapong PrachayasittikulPornlada NuchnoiMahidol University. Faculty of Medical Technology. Department of Clinical MicroscopyMahidol University. Faculty of Medical Technology. Center for Research and Innovation2017-08-232017-08-232017-08-232016Tropical Medicine and Health. Vol.44, (2016), 33https://repository.li.mahidol.ac.th/handle/20.500.14594/2761Cerebral malaria is still a deleterious health problem in tropical countries. The wide spread of malarial drug resistance and the lack of an effective vaccine are obstacles for disease management and prevention. Parasite and human genetic factors play important roles in malaria susceptibility and disease severity. The malaria parasite exerted a potent selective signature on the human genome, which is apparent in the genetic polymorphism landscape of genes related to pathogenesis. Currently, much genomic data and a novel body of knowledge, including the identification of microRNAs, are being increasingly accumulated for the development of laboratory testing cassettes for cerebral malaria prevention. Therefore, understanding of the underlying complex molecular basis of cerebral malaria is important for the design of strategy for cerebral malaria treatment and control.engMahidol UniversityCerebral malariaGeneticsPathogenesisMicroRNAOpen Access articleArticleBioMed Central10.1186/s41182-016-0033-6