Somnate BoonpucknavigPuangpen BenchachaiVijitr BoonpucknavigNatth BhamarapravatiMahidol UniversityFaculty of Medicine, Ramathibodi Hospital, Mahidol University2018-03-222018-03-221973-01-01Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.67, No.3 (1973), 410-415003592032-s2.0-0015863609https://repository.li.mahidol.ac.th/handle/20.500.14594/10133An immunofluorescent study of the malarial antigen in the tissues of mice infected with Plasmodium berghei (berghei strain) was conducted. In the first week of infection, the malarial antigen appears in corpuscular forms in the erythrocytes located in the vessels of the spleen, liver and kidney. From the second week onward, when antibodies to malaria begin to be detected, a new form of the malarial antigen, which appears as coarse granules, is detected in the fixed RE cells of the liver, spleen and in the glomerular endothelial and mesangial cells. There is a progressive decrease in the amount of the corpuscular form of the malarial antigen with a concomitant increase in the granular form. In the third week, most of the malarial antigen in the tissues is granular and the corpuscular form is rarely seen. © 1973.Mahidol UniversityImmunology and MicrobiologyMedicineArticleSCOPUS10.1016/0035-9203(73)90119-3