Severe dengue hemorrhagic fever after TAK-003 dengue vaccination: A case report of a potential vaccine-associated adverse reaction

Rattanaumpawan P.Horthongkham N.Suwannakarn K.Athipanyasilp A.Jongwutiwes U.Mahidol University2025-10-162025-10-162025-11-01International Journal of Infectious Diseases Vol.160 (2025)12019712https://repository.li.mahidol.ac.th/handle/123456789/112613We report a severe dengue case that developed symptoms 5 days post-TAK-003 dengue vaccine administration. Whole-genome sequencing confirmed co-detection of all four dengue serotypes with high similarity to vaccine strains, especially DENV-2. This finding warrants further investigation into a potential association with vaccine adverse events.MedicineSevere dengue hemorrhagic fever after TAK-003 dengue vaccination: A case report of a potential vaccine-associated adverse reactionArticleSCOPUS10.1016/j.ijid.2025.1080622-s2.0-1050180926591878351140946778