Chanchao LorthongpanichChuti LaowtammathronNittaya JiamvoraphongPimonwan SrisookPimjai ChingsuwanrotePhatchanat KlaihmonSupaporn WaeteekulYaowalak U-pratyaSurapol IssaragrisilFaculty of Medicine, Siriraj Hospital, Mahidol UniversityWattanosoth Hospital2020-08-252020-08-252020-10-01Stem Cell Research. Vol.48, (2020)18767753187350612-s2.0-85089190010https://repository.li.mahidol.ac.th/handle/20.500.14594/57672© 2020 The Authors In mammals, there are a number of kinases, including serine/threonine-protein kinase LATS1, that act as a core kinase of the Hippo pathway and that negatively regulate the Hippo effector protein YAP and its paralog TAZ. Using CRISPR/Cas9 technology, we established a stable LATS1 knockdown (LATS1-KD) iPSC from the MUSIi012-A cell line. The LATS1-KD iPSC MUSIi012-A-3 that was developed maintained both the normal karyotype and the pluripotent phenotype, and retained the ability to differentiate into all three embryonic germ layers.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyArticleSCOPUS10.1016/j.scr.2020.101950