α,α-Difluoro-α-phenylsulfanyl-α- trimethylsilylmethane as "cF<inf>2</inf><sup>-</sup>" synthetic building block for the preparation of gem-difluoromethylenated cyclopentanols

Krisana PeewasanChutima KuhakarnDarunee SoorukramPatoomratana TuchindaVichai ReutrakulManat PohmakotrMahidol University2018-06-112018-06-112012-03-01Journal of Fluorine Chemistry. Vol.135, (2012), 367-372002211392-s2.0-84857368913https://repository.li.mahidol.ac.th/handle/123456789/13780A general strategy for the preparation of gem-difluoromethylenated cyclopentanols has been demonstrated; it involves sequential fluoride-catalyzed nucleophilic addition of α,α-difluoro-α-phenylsulfanyl- α-trimethylsilylmethane (PhSCF 2 SiMe 3 ; 1) to homoallyl ketones followed by intramolecular radical cyclization. © 2011 Elsevier B.V. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryEnvironmental Scienceα,α-Difluoro-α-phenylsulfanyl-α- trimethylsilylmethane as "cF<inf>2</inf><sup>-</sup>" synthetic building block for the preparation of gem-difluoromethylenated cyclopentanolsArticleSCOPUS10.1016/j.jfluchem.2011.10.009