Jittra KornsakulkarnSiriporn SaepuaRapheephat SuvannakadSumalee SupothinaNattawut BoonyuenMasahiko IsakaSamran PrabpaiPalangpon KongsaereeChawanee ThongpanchangThailand National Center for Genetic Engineering and BiotechnologyMahidol University2018-12-212019-03-142018-12-212019-03-142017-01-01Tetrahedron. Vol.73, No.25 (2017), 3505-351214645416004040202-s2.0-85019462618https://repository.li.mahidol.ac.th/handle/20.500.14594/41991© 2017 Elsevier Ltd Twelve new compounds, including nine tropolones, nemanolones A−I (1–9), three 7-isochromenones, nemanecins A−C (10–12), and a new naturally isolated 4-isochromanone (13), along with two known compounds, 7,8-dihydroxy-3-methyl isochroman-4-one (XJP), and chaetoquadrin F, were isolated from culture broth of the fungus Nemania sp. BCC 30850. Structures of these compounds were elucidated by NMR and MS spectroscopic analyses. Nemanolones exhibited cytotoxic activities and two of them, compounds 1 and 2, also showed antibacterial activity against Bacillus cereus and antifungal activity against Candida albicans.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryArticleSCOPUS10.1016/j.tet.2017.05.030