Visasiri TantrakulChan Soon ParkChristian GuilleminaultMahidol UniversityStanford UniversityThe Catholic University of Korea2018-06-112018-06-112012-06-01Sleep Medicine. Vol.13, No.6 (2012), 656-66218785506138994572-s2.0-84861921190https://repository.li.mahidol.ac.th/handle/20.500.14594/14778Objective: To compare clinical manifestations and polysomnographic data of sleep-disordered breathing (SDB) in younger (less than 30. years old) versus older premenopausal women. Methods: A cohort of 420 premenopausal women diagnosed with SDB in a university sleep clinic during a 5-year period underwent systematic collection of clinical and polysomnographic variables. Results: One-hundred and fifteen (27.4%) women were younger than 30 (mean 24.5 ± 3.5. years), while 305 (72.6%) were older than 30 (mean 39.5 ± 5.7. years). The younger premenopausal women had less severe SDB with a trend towards upper-airway resistance syndrome. Despite similar daytime consequences, snoring was less common in the younger group. Both groups of premenopausal women frequently had insomnia and nasal abnormalities or craniofacial-deficiency. Conclusion: Recognizing the different clinical features and understanding the different polysomnographic presentation of SDB in young premenopausal women are crucial to detecting and treating this syndrome. © 2012 Elsevier B.V.Mahidol UniversityMedicineArticleSCOPUS10.1016/j.sleep.2012.02.008