Viboon BoonsarngsukAtcharaporn PongtippanSabaitip JuthakarnWison BoonsarngsukNoriaki KurimotoMahidol UniversitySt. Marianna University School of Medicine2018-09-132018-09-132009-10-01Journal of Bronchology and Interventional Pulmonology. Vol.16, No.4 (2009), 236-24019488270194465862-s2.0-70350179497https://repository.li.mahidol.ac.th/handle/20.500.14594/27909BACKGROUND: Traditionally, aspiration with high negative pressure is recommended to obtain a specimen in transbronchial needle aspiration (TBNA). Undeniably, however, the assistant experiences difficulty in the generation of the negative pressure and precise control of the syringe while performing the procedure. OBJECTIVE: To evaluate the effectiveness of the autoaspiration method created by our plunger lock in comparison with the conventional manual aspiration in the diagnosis of intrathoracic lymphadenopathy by TBNA. METHODS: A prospective study was conducted on all patients referred for diagnostic TBNA of enlarged intrathoracic lymph nodes. Both automatic and manual aspiration techniques were performed after the needle had been completely inserted into the nodes. The diagnostic yield and the numbers of diagnostic cells or benign lymphoid cells obtained by each technique were compared in the same node. RESULTS: A total of 31 intrathoracic lymph nodes in 24 patients were prospectively studied. Twenty-four nodes (77.4%) were malignancies whereas 7 nodes (22.6%) were benign disease. Adequate lymph node samples were obtained in 30 targets (96.8%), and TBNA revealed definite diagnosis for 25 nodes (80.6%). Both aspiration techniques showed exactly the same diagnostic yield. However, the autoaspiration technique provided significantly more adequate samples than manual aspiration techniques did (P=0.003). CONCLUSION: The autoaspiration method using our plunger lock was superior to the manual method in obtaining the numbers of adequate samples in TBNA procedures. Copyright © 2009 by Lippincott Williams & Wilkins.Mahidol UniversityMedicineArticleSCOPUS10.1097/LBR.0b013e3181b767e5