Hao Min ChengShao Yuan ChuangTzung Dau WangKazuomi KarioPeera BuranakitjaroenYook Chin ChiaRomeo DivinagraciaSatoshi HoshideHuynh Van MinhJennifer NailesSungha ParkJinho ShinSaulat SiddiqueJorge SisonArieska Ann SoenartaGuru Prasad SogunuruApichard SukonthasarnJam Chin TayBoon Wee TeoYuda TuranaNarsingh VermaYuqing ZhangJi Guang WangChen Huan ChenUniversity Medicine and Pharmacy, Hue UniversityDe La Salle Health Sciences InstituteSunway UniversityHanyang University Medical CenterJichi Medical UniversityYonsei University Health SystemShanghai Jiao Tong University School of MedicineMadras Institute of Orthopaedics and Traumatology HospitalsKathmandu UniversityUniversity of the East Ramon Magsaysay Memorial Medical CenterFatima Memorial HospitalNational Yang-Ming University TaiwanUniversitas Katolik Indonesia Atma JayaUniversitas IndonesiaUniversity of MalayaFuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical CollegeYong Loo Lin School of MedicineNational Taiwan University College of MedicineKing George's Medical UniversityVeterans General Hospital-TaipeiFaculty of Medicine, Siriraj Hospital, Mahidol UniversityNational Health Research Institutes TaiwanNational Yang-Ming University, School of MedicineTan Tock Seng HospitalChiang Mai University2020-05-052020-05-052020-03-01Journal of Clinical Hypertension. Vol.22, No.3 (2020), 391-40617517176152461752-s2.0-85076760103https://repository.li.mahidol.ac.th/handle/20.500.14594/54629© 2019 Wiley Periodicals, Inc. Since noninvasive central blood pressure (BP) measuring devices are readily available, central BP has gained growing attention regarding its clinical application in the management of hypertension. The disagreement between central and peripheral BP has long been recognized. Some previous studies showed that noninvasive central BP may be better than the conventional brachial BP in association with target organ damages and long-term cardiovascular outcomes. Recent studies further suggest that the central BP strategy for confirming a diagnosis of hypertension may be more cost-effective than the conventional strategy, and guidance of hypertension management with central BP may result in less use of medications to achieve BP control. Despite the use of central BP being promising, more randomized controlled studies comparing central BP-guided therapeutic strategies with conventional care for cardiovascular events reduction are required because noninvasive central and brachial BP measures are conveniently available. In this brief review, the rationale supporting the utility of central BP in clinical practice and relating challenges are summarized.Mahidol UniversityMedicineReviewSCOPUS10.1111/jch.13758