Xinjie GaiRonald GriggTossapol KhamnaenShuleewan RajviroongitVisuvanathar SridharanLixin ZhangSimon CollardAnn KeepUniversity of LeedsMahidol UniversityJohnson Matthey2018-07-242018-07-242003-09-29Tetrahedron Letters. Vol.44, No.40 (2003), 7441-7443004040392-s2.0-0042836595https://repository.li.mahidol.ac.th/handle/20.500.14594/20694A novel palladium-catalysed three component cascade process is described involving carbonylation of an aryl iodide to generate an acyl palladium species which is intercepted by a primary aliphatic/aromatic amine, amide or sulfonamide followed by intramolecular Michael addition to afford 3-substituted isoindolin-1-ones in good yield. © 2003 Elsevier Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1016/j.tetlet.2003.08.036