Feng ZhangJunbo GeJuying QianLei GeJun ZhouYuejin YangFang ChenXiaoling ZhuShuzheng LvZhizhong LiHaichang WangYin LiuYawei XuZhanquan LiHuigen JinWeiyi FangXuchen ZhouLijun JingYundai ChenChangyong ZhouZhexun LianYi AnYongjian YangZhixiong ZhongZuyi YuanXiaofei SunGuotai ShengZhenming YanRen Ke YiJian AnBin LiuZesheng XuXiaoqun PuYongwen QinShuangying FengGuosheng FuChunlin LaiBo YuTiemin JiangLefeng WangWeiming WangJianjun PengHui LiWenyue PangBiao XuHaiming ShiMeng WeiChangqian WangYing ZhuNingfu WangShaoliang ChenQiang FuShian HuangKeng WuYutian TongZheng ZhangGe ZhangHesong ZengHong JiangWenwei LiuGuoying ZhuPing LiXuekun ZhangZhimin DuYingfeng LiuWeimin LiLing LiuBen HeWei GaoDalin JiaJinchuan YanShaorong LiuChuanhuan ZhangYimin FangZhigang TaoJifu LiHe HuangXingui GuoXinghua ZhangTongbao LiuLianqun CuiJianming XiaoLianglong ChenJinfa JiangChenzhi LuXueqi LiPeng QuYan WangHonghua YeJingtian LiYuqing HouQiutang ZengYuanze JinDongju JiangKanghua MaDadong ZhangSuwatchai PornratanarangsiMuhamad MunawarTeguh SantosoFudan UniversityFuwai Cardiovascular HospitalBeijing Anzhen HospitalXijing HospitalTianjin Chest HospitalShanghai Tenth People's HospitalPeople's Hospital of Liaoning ProvincePutuo District Central Hospital of ShanghaiShanghai Chest HospitalDalian Medical UniversityGuangdong General HospitalPeoples' Liberation Army General HospitalQingdao University, School of MedicineChengdu Militar General HospitalMeizhou People's HospitalXi'an Jiaotong University, School of MedicineFirst People's Hospital of Jining CityJiangxi Provincial People's HospitalGeneral Hospital of Fushun Mining GroupShanxi Provincial Institute of Cardiovascular DiseaseJilin UniversityCangzhou Central HospitalXiangya Hospital of Zhongnan UniversityChanghai HospitalXingtai Cardiovascular Disease HospitalZhejiang UniversityShaanxi Provincial People's HospitalHarbin Medical UniversityArmed Police Medical College HospitalBeijing Red Cross Chaoyang HospitalPeking UniversityBeijing Shijitan General HospitalDaqing Oilfield General HospitalShengjing Hospital of China Medical UniversityThe Affiliated DrumTower Hospital of Nanjing University Medical SchoolShanghai Sixth People's HospitalXinhua HospitalHangzhou First People's HospitalNanjing First HospitalXuzhou Centre HospitalGuangdong Medical CollegeWeifang Yidu Zhongxin HospitalLanzhou UniversityKunming Medical CollegeHuazhong University of Science and TechnologyHubei General HospitalXiangfan City Central HospitalWuhan Asia Heart HospitalFirst People's Hospital of Yulin CityBeijing Luhe HospitalSun Yat-Sen UniversityZhujiang HospitalPeople's Hospital of Guangxi Zhuang Autonomous RegionRenji HospitalChina Medical University ShenyangJiangsu UniversityYantai Yuhuangding HospitalQilu Hospital of Shandong UniversityXiangtan Central HospitalHuadong HospitalShandong Provincial HospitalFujian Medical UniversityTongji UniversityTianjin First Central HospitalXiamen UniversityFirst People's Hospital of Ningbo CityWeifang Medical CollegeSouthern Medical UniversityWuhan Union HospitalThe 210th Hospital of PLAChongqing Medical UniversityShanghai Minhang District Central HospitalMahidol UniversityBina Waluya Cardiac HospitalMedistra Hospital2018-06-112018-06-112012-12-01EuroIntervention. Vol.8, No.8 (2012), 896-903196962131774024X2-s2.0-84872142061https://repository.li.mahidol.ac.th/handle/20.500.14594/14492Aims: The FOCUS registry is a prospective, multicentre, web-based programme designed to collect clinical outcome data from real-world patients receiving the second-generation cobalt-chromium sirolimus-eluting stent (CoCr-SES). Methods and results: From March 2009 to February 2010, a total of 5,084 patients from 83 centres who were eligible to receive CoCr-SES were enrolled in the FOCUS registry. The primary endpoint was 12-month major adverse cardiac events (MACE, defined as the composite of cardiac death, myocardial infarction [MI] , and target vessel revascularisation [TVR]). One-year data were available for 5,013 (98.6%) of the 5,084 patients enrolled. The primary endpoint occurred in 174 (3.47%) of 5,013 patients, consisting of 43 (0.86%) cardiac deaths, 132 (2.63%) MI, and 46 (0.92%) TVR. According to the Academic Research Consortium definition, definite and probable stent thrombosis (ST) occurred in 0.52% (26/5,013) of patients, including 19 cases of early ST and 7 of late ST. The 12-month MACE rates were 3.73% and 2.60% for extended-use and standard-use patients, respectively (p=0.065). Conclusions: The second-generation CoCr-SES was associated with low rates of 12-month MACE and ST in a broad spectrum of patients, thereby confirming the clinical safety and efficacy of this stent in a real-world setting. © Europa Digital & Publishing 2012. All rights reserved.Mahidol UniversityMedicineArticleSCOPUS10.4244/EIJV8I8A138